Fig. 1. Deficiency of Kir2.1 results in increased vessel density during retinal angiogenesis. (A) The images show increased total number of vessels and vessels density in P6 whole mount retinas in Kir2.1^+/- mice (IsoB4, white). The angiogenic front inset from the upper panel is shown enlarged in the lower panel. (B) Quantification of vasculature parameters in wild type and Kir2.1^+/- retinas as indicated. Each dot refers to the parameter of an individual mouse retina. Data are means of at least six mice per group. *P˂0.05. Scale bar panel A: 100 µm.